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HOT TOPICS IN VIRAL HEPATITIS: Issue 6, 2007
Hepatitis C transmission: current issues (Part One)
Sexual transmission of hepatitis C: controversies and facts
Virginie Masserey Spicher
Correspondence to:
Virginie Masserey Spicher - MD Doctor Division of Communicable Diseases Swiss Federal Office of Public Health Bern, Switzerland E-mail: Virginie.masserey@bag.admin.ch
Summary
- THE CONTROVERSIES
- THE FACTS
- Biological plausibility of sexual transmission
- Evidence that sexual transmission of HCV occurs
- Case reports
- Outbreaks
- Risk of sexual transmission of HCV
- Reported mode of transmission in newly diagnosed HCV infections
- Retrospective cohort studies
- Prevalence studies in populations with a higher risk of sexual exposure
- Factors associated with transmission
- Gender
- Age
- Viral load
- Genotype
- Stage or clinical status of liver disease
- Coinfections
- Sexually transmitted infections
- Mucosal damage
- Relationship duration
- Frequency and type of sexual activity
- High-risk sexual behavior
- DISCUSSION
- CONSEQUENCES
- Contribution to the burden of disease
- Recommendations for prevention
- Recommendations for screening
- REFERENCES
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