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HOT TOPICS IN CARDIOLOGY: Issue 1, 2006
Beta-blockers in heart failure: the state of the art
Beta-blockers in heart failure: the state of the art
Sian Harding, Alexander Lyon, Philip A. Poole-Wilson
Correspondence to:
Alexander Lyon - MA, BM, BCh, MRCP Cardiology Research Fellow Department of Cardiac Medicine National Heart and Lung Institute Imperial College London, UK E-mail: a.lyon@imperial.ac.uk
Summary
- HISTORY OF ADRENERGIC PHARMACOLOGY AND BETA-BLOCKER DEVELOPMENT
- β ADRENOCEPTORS
- β Adrenergic signalling in the normal cardiovascular system
- β ADRENERGIC SIGNALLING IN CARDIAC FAILURE
- β Adrenergic receptor function in cardiac failure
- β ADRENERGIC SECONDARY MESSENGER PATHWAYS IN CARDIAC FAILURE
- BETA-BLOCKERS AND RECEPTOR SELECTIVITY
- CLINICAL TRIALS OF BETA-BLOCKERS IN CARDIAC FAILURE
- CIBIS II-Bisoprolol [116]
- MERIT-HF-Metoprolol [122]
- COPERNICUS-Carvedilol [129]
- CAPRICORN-Carvedilol [134]
- SENIORS-Nebivolol [140]
- COMET-Carvedilol versus Metoprolol [145]
- THE FUTURE OF BETA-BLOCKERS IN CARDIAC FAILURE
- REFERENCES
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