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HOT TOPICS IN CARDIOLOGY: Issue 15, 2009
The vascular endothelium in hypertension: target and promoter?
The vascular endothelium in hypertension: target and promoter?
Andreas J. Flammer, Thomas F. Lüscher, Georg Noll, Jan Steffel, Isabella Sudano
Correspondence to:
Thomas F. Lüscher - MD, FRCP Professor and Chairman of Cardiology Cardiovascular Center Cardiology University of Zurich University Hospital Zurich Zurich, Switzerland E-mail: cardiotfl@gmx.ch
Summary
- ENDOTHELIAL FUNCTION IN HYPERTENSION
- ENDOTHELIAL-DERIVED VASODILATATING FACTORS
- Nitric oxide
- Prostacyclin
- Endothelium-derived hyperpolarizing factor(s)
- ENDOTHELIUM-DERIVED VASOCONSTRICTIVE FACTORS
- Endothelin
- Angiotensin
- Reactive oxygen species
- INFLAMMATION AND THROMBOSIS IN HYPERTENSIVE PATIENTS
- ANTIHYPERTENSIVE DRUGS AND ENDOTHELIAL FUNCTION
- Calcium antagonists
- Angiotensin-converting enzyme inhibitors
- Angiotensin II antagonists
- Beta-blocker
- CONCLUSION
- REFERENCES
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