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HOT TOPICS IN CARDIOLOGY: Issue 20, 2010
Oral antiplatelet agents: new insights in managing patients with acute coronary syndromes
Oral antiplatelet agents: new insights in managing patients with acute coronary syndromes
Marc P. Bonaca, Robert P. Giugliano
Correspondence to:
Marc P. Bonaca - MD TIMI Study Group Cardiovascular Medicine Harvard Medical School Brigham and Women’s Hospital Boston, MA, USA E-mail: mbonaca@partners.org
Summary
- BACKGROUND
- ASPIRIN
- Mechanism of action
- Pharmacokinetics and pharmacodynamics
- Drug interactions
- Side effects and contraindications
- Recent clinical trial findings
- P2Y12 INHIBITORS
- CLOPIDOGREL
- Pharmacokinetics and dosing
- Drug interactions
- Side effects and contraindications
- Recent clinical trial findings
- PRASUGREL
- Pharmacokinetics
- Drug interactions
- Side effects and contraindications
- Recent clinical trial findings
- TICAGRELOR
- Pharmacokinetics and pharmacodynamics
- Drug interactions
- Side effects and contraindications
- Recent clinical trial findings
- PROTEASE-ACTIVATING THROMBIN RECEPTOR-1 ANTAGONISTS
- Mechanism
- Pharmacokinetics and pharmacodynamics
- Drug interactions
- Side effects and contraindications
- Recent clinical trial findings
- Phase II Studies
- Phase III Studies
- SUMMARY
- REFERENCES
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